Comments on: Cell signaling pathways http://blog.cas-group.net/2009/01/cell-signaling-pathways/ Complex Adaptive Systems Group Fri, 11 May 2012 23:35:06 +0000 hourly 1 http://wordpress.org/?v= By: Rafe Furst http://blog.cas-group.net/2009/01/cell-signaling-pathways/comment-page-1/#comment-50 Rafe Furst Mon, 05 Jan 2009 04:26:05 +0000 http://blog.cas-group.net/?p=752#comment-50 While targeting pathways is better than targeting individual genes, it's not good enough. Cancer is a complex adaptive system and just because you find all extant pathways doesn't mean that the evolutionary process can't route around and create new pathways; that's what it does. The frontier in understanding cancer involves digging deeper into the complex evolutionary processes, and in particular looking at the genome level as opposed to the gene level. For those interested, I've posted a summary of some recent advances in this regard: <a href="http://rafefurst.wordpress.com/2009/01/01/cancer-as-evolution-2008-summary/" rel="nofollow">Cancer as evolution summary</a> While targeting pathways is better than targeting individual genes, it’s not good enough. Cancer is a complex adaptive system and just because you find all extant pathways doesn’t mean that the evolutionary process can’t route around and create new pathways; that’s what it does.

The frontier in understanding cancer involves digging deeper into the complex evolutionary processes, and in particular looking at the genome level as opposed to the gene level. For those interested, I’ve posted a summary of some recent advances in this regard:

Cancer as evolution summary

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